Can Sulfatrim cause diarrhea?

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Sulfamethoxazole and trimethoprim combination is used to treat infections such as urinary tract infections, middle ear infections (otitis media), bronchitis, traveler’s diarrhea, and shigellosis (bacillary dysentery). Sulfamethoxazole and trimethoprim combination is an antibiotic.
Side Effects. Nausea, vomiting, diarrhea, and loss of appetite may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria.
Like other antibiotics, Bactrim can change the natural balance of bacteria present in your gut and may cause a severe and persistent diarrhea, associated with a bacteria called Clostridium difficile. Contact your doctor if diarrhea develops either during treatment or within a couple of months of finishing treatment.

how long does Sulfatrim stay in system? The mean serum half-lives of sulfamethoxazole and trimethoprim are 10 and 8 to 10 hours, respectively. However, patients with severely impaired renal function exhibit an increase in the half-lives of both components, requiring dosage regimen adjustment (see DOSAGE AND ADMINISTRATION section).

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